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mCRP

monomeric CRP - mCRP
Class: Reference Ligands
Sub-class: GPVI Ligands - Collagen-Related Peptides
Sequence: GCO[GPO]10GCOG-NH2
M.W.: 3293.51

CRP-XL

Cross-linked monomeric CRP
Class: Reference Ligands
Sub-class: GPVI Ligands - Collagen-Related Peptides
Sequence: [[GCO[GPO]10GCOG-NH2]3]n
M.W.: N/A

GFOGER

GFOGER
Class: Reference Ligands
Sub-class: Integrin Ligands
Sequence: GFOGER in [GPP]5 and GPC
M.W.: 3704.21

vA3-III-23

Class: Reference Ligands
Sub-class: VWF A3-domain Ligands (also DDR 1 & 2 and SPARC)
Sequence: GPRGQOGVMGFO in [GPP]5 and GPC
M.W.: 4257

vA3-III-23Nle

Class: Reference Ligands
Sub-class: VWF A3-domain Ligands
Sequence: GPRGQOGVNleGFO in [GPP]5 and GPC
M.W.: 4239.89

GPP10

Class: Reference Ligands
Sub-class: Control Peptide
Sequence: GPC[GPP]10GPCG-NH2
M.W.: 3044

CLC II

Class: Collagen Ligands Collection
Sub-class: Collagen II
56 peptides coated on 96-well plates

CLC III

Class: Collagen Ligands Collection
Sub-class: Collagen III
57 peptides coated on 96-well plates

At present, we are able to supply Collagen II and Collagen III as sets of 56 and 57 peptides, in triplicate 96-well plates each arranged as in the schematic below.
Plates can be shipped to end-users for use in their own labs to map binding sites within these collagens. We add one additional plate for optimisation.




The Collagen Ligand Collection comes pre-coated on 96 well plates, in a ready-to-use adhesion assay format, and can be applied in solid-phase binding assays to map sites where collagen receptors and extracellular matrix components bind to collagens. Once a binding site is located, cycles of truncation and substitution allow exact residues involved to be determined, and corresponding minimal peptides to be synthesised for use in structural and functional studies.