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mCRP
monomeric CRP - mCRP
Class: Reference Ligands
Sub-class: GPVI Ligands - Collagen-Related Peptides
Sequence: GCO[GPO]10GCOG-NH2
M.W.: 3293.51
CRP-XL
Cross-linked monomeric CRP
Class: Reference Ligands
Sub-class: GPVI Ligands - Collagen-Related Peptides
Sequence: [[GCO[GPO]10GCOG-NH2]3]n
M.W.: N/A
OSCAR
OSCAR Ligands
Class: Reference and Activation Ligands
Sub-class: Osteoclast-Associated Receptor Ligands
Sequence: N/A
M.W.: N/A
CRP-QZ
Collagen-Related Peptide
Class: Reference Ligands
Sub-class: GPVI Ligands - Collagen-Related Peptides
Sequence: No Cys rest
M.W.: N/A
GFOGER
GFOGER
Class: Reference Ligands
Sub-class: Integrin Ligands
Sequence: GFOGER in [GPP]5 and GPC
M.W.: 3704.21
vA3-III-23
Class: Reference Ligands
Sub-class: VWF A3-domain Ligands
(also DDR 1 & 2 and SPARC)
Sequence: GPRGQOGVMGFO in [GPP]5 and GPC
M.W.: 4257
vA3-III-23Nle
Class: Reference Ligands
Sub-class: VWF A3-domain Ligands
Sequence: GPRGQOGVNleGFO in [GPP]5 and GPC
M.W.: 4239.89
GPP10
Class: Reference Ligands
Sub-class: Control Peptide
Sequence: GPC[GPP]10GPCG-NH2
M.W.: 3044
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CLC II
Class: Collagen Ligands Collection
Sub-class: Collagen II
56 peptides coated on 96-well plates
CLC III
Class: Collagen Ligands Collection
Sub-class: Collagen III
57 peptides coated on 96-well plates
At present, we are able to supply Collagen II and Collagen III as sets of 56 and 57 peptides,
in triplicate 96-well plates each arranged as in the schematic below.
Plates can be shipped to end-users for use in their own labs to map binding sites within these collagens.
We add one additional plate for optimisation.
The Collagen Ligand Collection comes pre-coated on 96 well plates, in a ready-to-use adhesion assay format,
and can be applied in solid-phase binding assays to map sites where collagen receptors and extracellular
matrix components bind to collagens. Once a binding site is located,
cycles of truncation and substitution allow exact residues involved to be determined,
and corresponding minimal peptides to be synthesised for use
in structural and functional studies.
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